Authors

Dr. Silvana Konermann is the cofounder and Executive Director of Arc Institute, as well as an Assistant Professor of Biochemistry at Stanford University. She is a pioneer in CRISPR-based technologies, including CRISPRa and CRISPR-Cas13d, which allow scientists to precisely manipulate gene and RNA expression and are critical to the development of the virtual cell. Her research focuses on the application of these technologies to neurodegenerative diseases, with the long-term goal of developing targeted therapeutics for Alzheimer’s disease.
Categories
Subscribe for updates
June 10, 2026
TED
The human cell is wildly complex. Can AI decode it?
Silvana Konermann and the team at Arc Institute are trying to crack one of science's most difficult problems: why complex diseases like Alzheimer's and cancer remain so stubbornly unsolvable, even as research advances. Her solution is a universal “virtual cell” — an AI model trained on a billion biological experiments that can read the language of human cells, predict what's going wrong and reveal how to fix it. In conversation with TED’s Chris Anderson, Konermann explores how this work could fundamentally change the way we discover drugs and treat disease. (This ambitious idea is part of The Audacious Project, TED’s initiative to inspire and fund global change.




